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Thallium imaging is historically significant as the epitome of myocardial perfusion imaging for decades, becoming a sort of ‘gold standard’ for its time.
Tl-201 scintigraphy is most often performed in conjunction with exercise stress in patients suspected or known to have CAD.
In addition to detection of stress-induced ischemia with exercise, the radionuclide test permits simultaneous assessment of regional myocardial viability.
The scintigraphic images obtained early after injection reflect the blood flow conditions at the time of tracer administration.
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